Nix Dermal cream 5 %

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What is Nix Dermal Cream

Nix Dermal Cream is an effectively used, normally safe treatment for scabies.

How does Nix Dermal Cream Work:

Nix Dermal Cream kills scabies mites and their eggs, which effectively stops the intense itching and skin breakouts (lesions) that mites cause.

How is Nix Dermal Cream used:

Nix Dermal Cream should be applied to clean, dry, cool skin, applying from the neck down to the bottom of the feet. Extra care should be given to the areas between the fingers and toes, underarms, the genital area and buttocks, anywhere on the body that the mites or their eggs can hide.

Side Effects

Occasional worsening of the itching and redness from the scabies is possible as well as a slight burning sensation. Numbness, tingling and rash are also a possible side effect and there have been some reports of eczema and edema.

Other Brand Names

While there is no other brand name for Nix Dermal Cream, there is a lotion form called Kwellada-P that is manufactured by the same company and is available in Canada. Both products contain 5% Permethrin.

Safety Information:

Nix Dermal Cream should not be used by anyone under two years of age without consulting a physician. Pregnant women and nursing mothers should consult their doctor before using Nix Dermal Cream. Anyone having allergies to the ingredients in Nix Dermal Cream including: synthetic yrethroid, pyrethrin or chrysanthemums should not use the product.

Dosage:

Nix Dermal Cream comes in a 30g size, 5% Permethrin, cream formula and is to be used externally only. The cream should be applied once and left on for 12-14 hours. If the hands are washed before the 12-14 hours are completed it may be reapplied to the hands. After the treatment is complete, the body should be bathed completely and clean clothes may be worn. After 7-10 days if lives mites are present or new skin lesions have appeared, a second application would be necessary.

Visual Description:

Nix Dermal Cream is packaged in a white and gray package with a pink stripe on the front with "Nix" on the front, left corner of the package.

Directions for Use

1. Clean and dry skin.

Note: Do not take a hot bath before treatment.

2. Apply sufficient amounts of Nix dermal cream (30 g) and thoroughly massage cream from the head to the soles of the feet, paying special attention to creases in the skin, hands, feet, between fingers and toes, underarms and groin. Put on clean clothes. Long-sleeved shirts, pants and mittens should be worn by young children to avoid contact with mouth.

3. Leave Nix dermal cream on skin for 12 to 14 hours.

4. Wash off by taking a shower or a bath.

5. Change into clean clothes.

6. Scabies will be killed, but itching may persist. This is normal and should not be interpreted as treatment failure.

7. One single application is effective in most cases. If necessary, a second application may be given 7 to 10 days after the first, but only if live mites can be demonstrated or new lesions appear.

8. To reduce the risk of transmission or eliminate reinfestation, it is recommended that family members and close contacts, including sexual partners, be treated with Nix dermal cream.

9. All clothing, bed linens, and towels used within the 2 days prior to treatment should be machine-washed in hot water and dried on dryer hot cycle for at least 20 minutes, or dry cleaned following treatment. Mattresses which have been used by an infested person should not be used for 48 hours. Toilet seats should be disinfected.

10. Discontinue use of other topical medications and cosmetics during treatment.

Precautions

General: Scabies infestation is often accompanied by itching, redness and swelling. Treatment with Nix dermal cream may temporarily worsen these symptoms. Do not use this product if you are allergic to any of its ingredients, to synthetic pyrethroids or pyrethrins, or to chrysanthemums. Discontinue use if a reaction occurs. Pruritus (itching) caused by an acquired sensitivity to mites and their products frequently persists for one to several weeks following treatment with the drug. This reaction does not indicate treatment failure. Retreatment is only necessary if live mites appear or new lesions develop.

Eye Irritation: Permethrin is not an eye irritant, but contact of Nix dermal cream with the eyes should be avoided because the cream itself may cause marked irritation. If it should get into eyes, rinse them immediately with plenty of water or, if readily available, normal saline.

In Case of Swallowing: Consult your physician or a Poison Control Centre.

Use in Pregnancy: Studies have been performed in rats and rabbits and have revealed no evidence of reduced fertility or harm to the fetus due to permethrin. Negative in vivo genotoxicity tests and the very low mammalian toxicity would suggest that any risk to the fetus following treatment with Nix dermal cream is minimal. There are, however, no adequate or well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only after consulting your physician.

Lactation: It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, and because of the evidence for tumorigenic potential of permethrin in some animal species, consideration should be given to discontinuing nursing temporarily or not using the drug while nursing.

Children: Nix dermal cream is safe and effective in children 2 years of age and older. Before using in children under 2 years of age, consult your physician.

Keep out of the reach of children. In order to prevent accidental ingestion by children, the remaining contents of Nix should be discarded after use.

Adverse Reactions

In clinical studies, occasional itching has occurred. This is usually a consequence of the scabies infestation itself, but may be temporarily worsened following treatment with Nix. Other reactions which are less frequent include: mild, temporary stinging/burning, tingling, numbness or skin discomfort, redness, and swelling or rash of the skin.