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Kwellada-p Creme rinse 1 %
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Kwellada Creame Rinse

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What does Kwellada-P Creme Rinse contain?

1% permethrin as the active ingredient.

When should you use Kwellada-P Creme Rinse?

Kwellada-P Creme Rinse is indicated for the treatment of head lice (Pediculus capitis). It kills head lice and their nits (eggs) on contact.

When should you not use Kwellada-P Creme Rinse?

It is not to be used on individuals with known sensitivities or reactions to permethrin, any synthetic pyrethroid or pyrethrins, or to chrysanthemums. If you are pregnant or nursing, consult your physician before using Kwellada-P creme rinse.

Consult your physician before using Kwellada-P creme rinse in children under the age of 2 years.

What precautions should you take?

Avoid contact with eyes, nose, mouth and other mucous membranes as well as wounds and broken skin. This product may irritate your eyes. In case of contact, rinse with plenty of water. If skin irritation occurs, discontinue use and consult your doctor. If swallowed, contact your doctor or Poison Control Centre.

How should you use Kwellada-P?

Shampoo the hair with a conditioner-free shampoo. Rinse with water and thoroughly towel dry.
Shake Kwellada-P creme rinse well before using.
With scissors, snip off the top of the enclosed applicator cap.
Unscrew cap on bottle and replace with the applicator cap.
Apply Kwellada-P creme rinse to damp hair. Apply sufficient amount to saturate hair and scalp (25 to 50 mL).
Leave on for 10 minutes.
Rinse thoroughly with water and dry with towel.
Remove dead lice and eggs with the following steps: Comb wet hair with a regular comb to remove snarls; separate a strand of hair not wider than the nit comb. Using the enclosed nit comb tilted toward the scalp, comb the strand from scalp to end of hair; repeat to remove all eggs, comb all strands in this manner.
Store unused product by removing the applicator cap from the bottle and replacing it with the original cap. Rinse and air dry.
A single application is usually sufficient but a second application may be required 7 days after the first application if you see live lice or nits (eggs).

How should you store Kwellada-P?

Store the product between 15 and 30°C.

What are head lice?

Head lice are tiny insects that live in human hair. They hatch from small eggs, called nits, which are attached to the base of individual hairs. The eggs hatch in about 7 to 10 days, with the new lice reaching maturity about 14 days later. The female louse can live for 20 to 30 days, and can lay as many as 6 eggs a day. Since lice multiply fast, they should be treated promptly.

Who suffers from head lice?

Getting head lice is not as bad as you think. It is not a sign of uncleanliness, or poor health habits. Head lice can occur at any age, and to either sex, so it is wise to learn how to recognize a head lice infestation and how to prevent it from coming back.

How does someone get head lice?

Head lice can be transmitted in a number of ways besides direct head to head contact. Borrowing a comb or brush from a person who has head lice will do it. So can borrowing hats, ribbons, scarves or other head coverings. Sharing towels or pillows can also spread head lice. Even a stray hair that has nits can transmit head lice.

What signs should I look for?

Persistent itching of the back of the head and behind the ears can indicate head lice. You should also look for infected scratch marks or a rash on the scalp. Most important of all, look for nits attached to individual hairs at scalp level. These can be seen with the naked eye, but you can probably identify them more easily with the aid of a magnifying glass under strong light. Sometimes small white specks in the hair such as dandruff or droplets of hair spray can be confused with nits. Try removing the specks from the hair shaft. Dandruff or hair spray will come off easily—nits are very difficult to remove. Check with a health professional if you are not sure whether head lice are present.

Should other family members be checked?

Yes. If one member of your family has head lice, all household members and sexual partners should be checked and, if necessary, treated.

How can I prevent head lice in the future?

All family members should avoid borrowing personal items (combs, brushes, hats, towels or clothing) from each other or from friends. It is best for everyone to use his or her own personal articles, both at home and while away.

Technical Information

Information for the Patient

Kwellada-P Creme Rinse

Pharmacology

Permethrin, a synthetic pyrethroid, has a broad spectrum of insecticidal activity combined with high potency when applied topically to insects, including head lice, Pediculus capitis.

Like other pyrethroids, permethrin is a sodium channel toxin. In susceptible nerve cells small amounts of permethrin cause a change in the kinetics of the sodium channel. Although the activation of the sodium current is unaffected, the rate of inactivation of the current is greatly slowed. This tail current, even at low doses, is adequate to cause repetitive activity. One normal action potential, in the presence of permethrin, leads to a series of abnormal action potentials. Consequently, there is repetitive firing of the neuron.

Studies, both in vitro and in vivo, have demonstrated that permethrin is active against both the adults and eggs of head lice. In clinical trials 1% permethrin was found to be an efficacious treatment for head lice. After 1 treatment, over 98% of patients were free of head lice at 7 days and over 93% of patients were free of lice at 14 days, indicating that permethrin continues to exert activity after treatment. In the same study, fewer than 2% of patients had viable eggs 7 days after a single application of 1% permethrin creme rinse and at 14 days less than 4% of patients had viable eggs.

Indications

For the treatment of Pediculus capitis, including adults, nymphs and eggs. One application is usually adequate to eradicate the infestation of head lice. Should reinfestation occur, or the first application not completely eradicate the head lice, a second treatment should be administered 7 days after the initial treatment.

Precautions

Lactation

Children

General

Pregnancy

Supplied

Each mL of creme rinse liquid contains: permethrin 1% w/w cis/trans ratio of 25:75. Nonmedicinal ingredients: carbomer 980, isopropyl alcohol, lauryl alcohol, polyoxyethylene 4 lauryl ether, polyquarternium-24, propylene glycol, purified water, stearalkonium chloride and trolamine. Plastic bottles of 50 and 200 mL. Store between 15 and 30°C.

Contraindications

Patients with a known sensitivity or reaction to permethrin, any synthetic pyrethroid or pyrethrins, or to chrysanthemums.

Warnings

Should be discontinued if hypersensitivity occurs.

Adverse Effects

Clinical trials have indicated that adverse reactions are reported infrequently. Adverse reactions which do occur are usually mild and resolve rapidly. They are local in nature.

In clinical trials pruritus was the most frequently reported adverse event with fewer than 3% of patients reporting it. The next most frequently reported adverse event was burning and stinging followed by erythema, which was reported by less than 1% of patients.

Overdose

Symptoms

Treatment

Dosage

After the hair has been shampooed, rinsed and towelled dry, apply enough creme rinse to saturate the hair and scalp, between 25 to 50 mL. Leave on for 10 minutes. The creme rinse should then be thoroughly rinsed off with water and the hair towelled dry. Nits can be combed out with the comb provided, if desired.

One treatment is usually adequate to eliminate the head lice.

Kwellada-P should be shaken before use.

Kwellada-p Creme rinse 1 %

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