Xatral Medication Information:

Price Break On Xatral
Generic is available for less money: Generic Alfuzosin

Xatral medication comes in several different strengths; click on the strength you need to view prices from pharmacies competing to earn your business.

Xatral 2.500 mg
Xatral 5 mg
Xatral 10 mg
Xatral XL 10 mg

Xatral General Information

Xatral contains alfuzosin hydrochloride and belongs to a group of medications called alpha 1A receptor antagonists and is used to treat the symptoms and signs of benign prostatic hyperplasia (enlargement of the prostate) which causes a decrease of urine flow in men.

How does Xatral work & what does it do?

In men the prostate gland often enlarges with age unfortunately pressing on the urethra and obstructing the flow of urine from the bladder. Xatral relaxes the muscles in the prostate and also the opening of the bladder. This may help to increase the flow of urine and decrease the symptoms of benign prostatic hyperplasia.

When/How is Xatral taken/used/applied?

Xatral should be taken as a 10mg tablet daily preferably after a meal. The pill should be ingested whole and should not be crushed or chewed in any way and should be taken after the same meal around the same time every day.

Side Effects of Xatral

Most medications have side effects and are usually mild enough that it does not deter from the utility of the drug. The most common side effects of Xatral are: runny nose, sore throat, coughing, and dizziness. Less common side effects are: nausea, indigestion, headache, fatigue, constipation, back pain, and decreased sexual drive.

Other Brand Names for Xatral:

Another brand name for Xatral is Alfuzosin which is it's marketing name in the United States.

Safety Information:

There are several groups of people who should not take Xatral:
Anyone who has moderate to severe impairment of liver function.
Women and children should not use Xatral.
Anyone who has an allergic reaction to any of the ingredients of the medication.


The dosage is in pill form and is 10mg strength.

Visual Description:

The 10 mg pill is a middle white matrix layer between two inactive yellow layers.

About Xatral

What Xatral is used for

Your doctor has prescribed XATRAL because you have a medical condition called benign prostatic hyperplasia (BPH) or acute urinary retention (AUR) related to BPH. This occurs in men.

What Xatral does

XATRAL relaxes muscles in the prostate, bladder neck and base. This results in improved urine flow, and reduced BPH symptoms.

When taken during catheterization for sudden acute urinary retention, XATRAL may help you pass urine after catheter removal. Urinary catheters are flexible tubes placed in the bladder to drain urine.

When Xatral should not be used

If you have ever had an allergic reaction to alfuzosin hydrochloride or to any ingredient in XATRAL (see What the important nonmedicinal ingredients are:).

If you have a moderate to severe decrease in liver function.

If you take other alpha1-blockers for high blood pressure or prostate problems.

If you take ketoconazole, ritonavir (Kaletra; Norvir) or itraconazole (Sporanox).

What the medicinal ingredient is


What the important nonmedicinal ingredients for Xatral are

Colloidal hydrated silica, ethylcellulose, hydrogenated castor oil, hydroxypropyl methylcellulose, magnesium stearate, mannitol, microcrystalline cellulose, povidone, yellow ferric oxide.

What dosage forms Xatral comes in

Prolonged-release tablets. Each tablet contains 10 mg alfuzosin hydrochloride.

Warnings and Precautions

XATRAL is not indicated as a treatment to lower blood pressure.

XATRAL is not indicated nor recommended for use in women and children.

Prostate cancer and BPH cause many of the same symptoms. Prior to starting XATRAL, your doctor will examine you to rule out the presence of prostate cancer.

You (in particular, if you are receiving drugs to lower blood pressure) may experience low blood pressure and feel dizzy at the start of treatment, especially when getting up from a lying or sitting position. In such cases, lie down until the symptoms have completely disappeared.

Tell your doctor or pharmacist, before using the medication, if:

  • you suffer liver or kidney problems.

  • you suffer from heart problems.

  • you have ever had a reaction to the ingredients of this medication.

  • You have had low blood pressure or signs of low blood pressure [fainting, dizziness] after taking another medicine.

  • You or any family members have a condition known as congenital prolongation of the QT interval.

  • You have suffered from QT prolongation following the administration of any drug.

  • You have a family history of sudden death at an age <50 years.

  • You have suffered from electrolytes disturbances.

If you will have eye surgery, you must inform your eye surgeon that you are currently using XATRAL.

Interactions with Xatral

XATRAL is metabolized by specific enzymes in the liver. It is not known how combined use of any drugs, herbal products metabolized by the same enzymes or grapefruit juice may influence the efficacy or unwanted side effects of these drugs or herbal medicines.

Before using any prescription, over-the-counter medicines or herbal products, check with your doctor or your pharmacist.

Drugs that interact with XATRAL include:

  • Alpha1-blockers for high blood pressure or prostate problems.

  • Anti-infection drugs: ketoconazole, itraconazole (Sporanox) and ritonavir (Kaletra; Norvir ).

  • Drugs for high blood pressure.

  • Drugs for heart problems (nitrates).

  • Sildenafil (Viagra, Revatio).

Proper Use of Xatral

Usual dose

Follow your doctor's instructions very carefully about how to take XATRAL.

The recommended dosage is one tablet (10 mg) daily to be taken right after the same meal each day or from the first day of catheterization. The tablet should be swallowed whole.


If you interrupt your treatment for several days or more, resume treatment after consulting with your doctor.


If you have taken too much XATRAL, immediately see your doctor or go to your nearest hospital emergency department or contact poison control centre. Show the doctor your bottle of tablets. Do this even if there are no signs of discomfort or poisoning. Overdose of alfuzosin may lead to low blood pressure.

Side Effects for Xatral and What to Do About Them

Like all prescription drugs, XATRAL may cause side effects. Most side effects are mild.

Side effects due to XATRAL may include dizziness and headache. In some cases, side effects may decrease or disappear while the patient continues to take XATRAL.

You may experience dizziness or fainting caused by a decrease in blood pressure after taking XATRAL. However, these effects are usually transient, occur at the beginning of treatment and do not usually prevent the continuation of treatment. In such cases, lie down until the symptoms have completely disappeared. Although these symptoms are unlikely, do not drive, operate machinery or perform hazardous tasks for 12 hours after the initial dose.

Cases of liver disorder have been observed in patients taking XATRAL. You should inform your doctor if you experience symptoms such as nausea, fatigue, jaundice (yellow colour to the skin and/or eyes), dark urine, light-coloured stools, generalised itching or abdominal pain.

Cases of priapism (painful erection greater than 6 hours) have been rarely reported with the use of XATRAL. If you experience painful erection lasting more than 4 hours, you should contact your doctor immediately. If priapism is not immediately treated, penile tissue damage and erectile dysfunction could result.

Serious Side Effects, How Often They Happen and What to Do About Them
Symptom/Effect Talk with your doctor or pharmacist Stop taking drug and call your doctor or pharmacist
Only if severe In all cases
Common Headache    
Uncommon Fainting    
Liver disease    
Priapism/erection lasting longer than 4 hours    

This is not a complete list of side effects. For any unexpected effects while taking XATRAL, contact your doctor or pharmacist.

Xatral Facts

The active ingredient in Xatral was approved by the FDA for treatment of benign prostatic hyperplasia (BPH) in June 2003.

Xatral is marketed in the United States using the trade name Uroxatral.

Xatral is a trade name for a medication containing the active ingredient alfuzosin.

Xatral belongs to a group of medications known as alpha 1A receptor antagonists.


Technical Information