Prozac Medication Information:

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Prozac medication comes in several different strengths; click on the strength you need to view prices from pharmacies competing to earn your business.

Prozac 10 mg
Prozac 20 mg

About Prozac

What Prozac is used for

PROZAC has been prescribed by your doctor to relieve your symptoms of:

  • depression (feeling sad, a change in appetite or weight, difficulty concentrating or sleeping, feeling tired, headaches, unexplained aches and pain)

  • bulimia (eating disorder, characterized by self-induced vomiting after eating)

  • or obsessive-compulsive disorder (recurrent and intrusive thought, feeling, idea, or sensation; recurrent pattern of behaviour, or unwanted thoughts or actions)

What Prozac does

PROZAC belongs to a group of medicines called selective serotonin reuptake inhibitors (SSRIs). PROZAC is thought to work by increasing the levels of a chemical in the brain called serotonin (5-hydroxytryptamine).

When Prozac should not be used

Do not use PROZAC if you are:

  • allergic to it or any of the components of its formulation (see The important nonmedicinal ingredients are:).

  • currently or have recently taken the drug thioridazine.

  • currently or have recently taken monamine oxidase antidepressants (e.g. phenelzine sulphate, moclobemide).

The medicinal ingredient is

PROZAC Capsules contain the active ingredient fluoxetine hydrochloride.

The important nonmedicinal ingredients for Prozac are

PROZAC 10 mg and 20 mg capsules contain benzyl alcohol, butylparaben, carboxymethylcellulose sodium, edetate calcium disodium, FD&C Blue No. 1, gelatin, iron oxide yellow, methylparaben, propylparaben, silicone, sodium propionate, sodium lauryl sulfate, starch, and titanium dioxide.

There is no gluten, lactose, sulfite, or tartrazine in PROZAC.

What dosage forms Prozac comes in

PROZAC Capsules are available in 10 mg (green) and 20 mg (green and yellow) strengths.

Warnings and Precautions

During treatment with these types of medications, it is important that you and your doctor have good ongoing communication about how you are feeling.

PROZAC is not for use in children under 18 years of age.

New or Worsened Emotional or Behaviour Problems

Particularly in the first few weeks or when doses are adjusted, a small number of patients taking drugs of this type may feel worse instead of better; for example, they may experience unusual feelings of agitation, hostility or anxiety, or have impulsive or disturbing thoughts such as thoughts of self-harm or harm to others. Should this happen to you, or those in your care if you are a caregiver or guardian, consult your doctor immediately, do not discontinue your medication on your own.

Before starting PROZAC, tell your doctor or pharmacists:

  • if you have ever had an allergic reaction to any medication

  • all your medical conditions, including a history of liver or kidney problems, seizures or blackouts, diabetes, and heart problems or abnormal bleeding

  • any medications (prescription or nonprescription) you are taking or have recently taken, especially monoamine oxidase (MAO) inhibitors (e.g., phenelzine sulfate, tranylcypromine sulfate, moclobemide or selegeline) or thioridazine

  • any natural or herbal products you are taking (e.g. St. John's Wort)

  • if you are pregnant or thinking about becoming pregnant, or if you are breast feeding

  • your habits of alcohol and/or street drug consumption

  • if you drive a vehicle or perform hazardous tasks during your work

Effects on Pregnancy and Newborns

Post-marketing reports indicate that some newborns whose mothers took an SSRI (selective serotonin reuptake inhibitor) or other newer antidepressant, such as PROZAC, during pregnancy have developed complications at birth requiring prolonged hospitalization, breathing support and tube feeding. Reported symptoms included feeding and/or breathing difficulties, seizures, tense or overly relaxed muscles, jiterriness and constant crying.

In most cases, the newer antidepressant was taken during the third trimester of pregnancy. These symptoms are consistent with either a direct adverse effect of the anti-depressant on the baby, or possibly a discontinuation syndrome caused by sudden withdrawal from the drug. These symptoms normally resolve over time. However, if your baby experiences any of these symptoms, contact your doctor as soon as you can.

If you are pregnant and taking an SSRI, or other newer antidepressant, you should discuss the risks and benefits of the various treatment options with your doctor. It is very important that you do NOT stop taking these medications without first consulting your doctor. See Side Effects and What to do About Them: for more information.

Interactions with Prozac

Do not use PROZAC if you are taking or have recently taken monoamine oxidase (MAO) inhibitors or thioridazine.

You should tell your doctor if you are taking or have recently taken any medications (prescription, nonprescription or natural/herbal), especially:

  • other antidepressants, such as SSRIs, certain tricylics, drugs used to treat schizophrenia, or bipolar depression (e.g. lithium)

  • drugs which may affect blood clotting and increase bleeding, such as drugs used to thin the blood (anticoagulants, e.g. warfarin), as well as acetylsalicylic acid (e.g. Aspirin) and other non-steroidal anti-inflammatory drugs (e.g. ibuprofen)

  • certain medicines used to treat patients with irregular heart beats

  • certain drugs used to treat diabetes

  • other drugs that affect serotonin, such as lithium, linezolid, tramadol, drugs containing tryptophan, St. Johns Wort, triptans used to treat migraines

  • sedatives such as benzodiazapines

As with many drugs that work directly on the brain, use of alcohol while taking PROZAC should be limited/moderate.

Proper Use of Prozac

Usual dose

  • It is very important that you take PROZAC exactly as your doctor has instructed. Generally people take between 20 mg to 80 mg per day for depression and obsessive-compulsive disorder and between 20 and 60 mg per day for bulimia.

  • PROZAC is usually taken once a day. It may be taken with or without food. If you are taking capsules, you should swallow the capsules whole; do not chew them.

  • You should continue to take your medicine even if you do not feel better, as it may take a number of weeks for your medicine to work.

  • Keep taking your PROZAC until the doctor tells you to stop.

  • Talk to your doctor before you stop taking your medication on your own.

Remember: This medicine has been prescribed only for you. Do not give it to anybody else, as they may experience undesirable effects, which may be serious.


If you have taken a large number of tablets all at once, contact your doctor, the regional Poison Control Centre, or the nearest hospital emergency department immediately, even though you may not feel sick. Show the doctor your prescription bottle.

Missed dose

If you forget to take a dose of PROZAC, take it as soon as you remember. Take your next dose at the next scheduled time; do not try to make up for a missed dose by taking a double dose the next time.

Side Effects for Prozac and What to do About Them

Like other medications, PROZAC can cause some side effects. You may not experience any of them. For most patients, side effects are likely to be minor and temporary. However, some may be serious. Some of these side effects may be dose related. Consult your doctor if you experience these or other side effects, as the dose may have to be adjusted.

The most common side effects of PROZAC are:

  • nausea

  • dizziness

  • headache

  • anxiety

  • nervousness

  • drowsiness

  • insomnia (difficulty falling or staying asleep)

  • fatigue

  • weakness

  • diarrhea

  • upset stomach

  • dry mouth

  • loss of appetite

  • excessive sweating

PROZAC does not usually affect people's normal activities. However, some people feel sleepy while taking it, in which case they should not drive or operate machinery.

Although psychiatric disorders may be associated with decreases in sexual desire, performance and satisfaction, treatment with this medication may also affect sexual functioning.

New or Worsened Emotional or Behaviour Problems

A small number of patients taking a drug of this type may feel worse instead of better, such as experiencing new or worsened feelings of agitation, hostility, anxiety, or thoughts about suicide. Your doctor should be informed of such changes immediately. Close observation by a doctor is necessary in this situation. Do not discontinue your medication on your own. See also the Warnings and Precautions: section.

Discontinuation Symptoms

Contact your doctor before stopping or reducing your dosage of PROZAC. Symptoms such as headache, insomnia, paresthesias (numbness, tingling, burning, or prickling sensation) nervousness, anxiety, nausea, sweating, dizziness, jitteriness and weakness and other symptoms have been reported after stopping PROZAC. These symptoms usually disappear without needing treatment. Tell your doctor immediately if you have these or any other symptoms. Your doctor may adjust the dosage of PROZAC to alleviate the symptoms. See Warnings and Precautions: section for more information.

Effects on Newborns

Some newborns whose mothers took an SSRI (Selective Serotonin Uptake Inhibitor) or other newer antidepressants during pregnancy have shown such symptoms as breathing and feeding difficulties, jitteriness and constant crying. If your baby experiences any of these symptoms, contact your doctor as soon as you can. See Warnings and Precautions: section for more information.

The following table is based on data from placebo-controlled clinical trials involving 10 782 patients.

Serious Side Effects, How Often They Happen and What to do About Them
Symptom/Effect Talk with your doctor or pharmacist Stop taking drug and call your doctor or pharmacist
Only if severe In all cases
Common Allergic reactions (skin rash, hives, swelling, trouble breathing)     a
Uncommon Bruising or unusual bleeding from the skin or other areas    
Hallucinations [strange visions or sounds]    
Inability to urinate    
Akathisia [feeling restless and unable to sit or stand still]    
Seizures [i.e. loss of consciousness with uncontrollable shaking (“fit”)]     a
Mania [overactive behaviour and thoughts]    
Rare Gastrointestinal bleeding [vomiting blood or passing blood in stools]   a  
Increased pressure in the eyes [symptoms of eye pain and blurred vision]    
Liver disorder [symptoms include nausea, vomiting, loss of appetite combined with itching, yellowing of the skin or eyes, dark urine]   a  
Uncontrollable movements of the body or face    
Low sodium level in blood [symptoms of tiredness, weakness, confusion combined with achy, stiff or uncoordinated muscles]    
Very Rare Serotonin syndrome [a combination of most or all of the following; confusion, restlessness, sweating, shaking, shivering, hallucinations, sudden jerking of the muscles, fast heartbeat]   a  
See Warnings and Precautions: New or worsened emotional or behavioural problems   a  
a. If you think you have these side effects, it is important that you seek medical advice from your doctor immediately.

This is not a complete list of side effects. For any unexpected effects while taking PROZAC, contact your doctor or pharmacist.


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