Symbicort

Symbicort Medication Information:

Price Break On Symbicort
Generic is available for less money: Generic Formoterol/Budesonide Inhaler

Symbicort medication comes in several different strengths; click on the strength you need to view prices from pharmacies competing to earn your business.

Symbicort 100mcg/6mcg
Symbicort Aerosol Inhaler 160-4.5mcg, 10.2gm Inhaler
Symbicort 200mcg/6mcg
Symbicort 400mcg/12mcg

About Symbicort

What Symbicort is used for

SYMBICORT TURBUHALER contains a mixture of the medicines budesonide and formoterol to treat asthma in adults and children (i.e. 12 years and older) and Chronic Obstructive Pulmonary Disease (COPD) in adults (i.e. 18 years and older).

Asthma

Asthma is a chronic disease of the lungs caused by inflammation which causes narrowing of the airways and increased mucus production. Symptoms such as chest tightness, wheezing, coughing and difficulty in breathing are common. These symptoms become more pronounced during periods of disease worsening or an asthma attack due to the narrowing of the airways.

SYMBICORT TURBUHALER should only be used when your doctor decides that other asthma medications (i.e. inhaled glucocorticosteroids along with an as needed relief medication) are not helping you enough, or that you need two maintenance medications to control your asthma. SYMBICORT TURBUHALER should not be the first medication you use, unless advised by your doctor.

COPD

Chronic Obstructive Pulmonary Disease (COPD) is also referred to as chronic bronchitis and emphysema. COPD is a chronic lung disease largely caused by cigarette smoking. COPD leads to a narrowing and persistent inflammation of the airways, increased mucous production and damage to the lungs. This results in breathing difficulties and a feeling of breathlessness. Symptoms such as coughing, breathlessness, mucous production and coughing and wheezing can become intense during periods of disease worsening.

What Symbicort does

Budesonide is a corticosteroid that reduces and prevents this airway inflammation. Formoterol widens your airways by relaxing the airway muscles, making it easier for you to breathe. This effect starts within 1-3 minutes after you have inhaled the medicine and lasts for up to 12 hours. When you breathe in through the mouthpiece of the inhaler, the medicine follows your breath to your lungs.

Regular use of SYMBICORT TURBUHALER gives 24-hour relief or prevention of symptoms such as shortness of breath in patients with asthma, COPD and other similar conditions (see Proper Use of This Medication:).

When Symbicort should not be used

If you are allergic to budesonide, formoterol or inhaled lactose.

What the medicinal ingredients for Symbicort are

SYMBICORT TURBUHALER is a dry powder inhalation device that contains formoterol fumarate dihydrate and budesonide.

What the nonmedicinal ingredient is

Lactose (may contain milk protein).

What dosage forms Symbicort comes in

SYMBICORT TURBUHALER is supplied in two strengths:

SYMBICORT 100 TURBUHALER (100/6 µg budesonide/formoterol fumarate dihydrate per dose),

SYMBICORT 200 TURBUHALER (200/6 µg budesonide/formoterol fumarate dihydrate per dose) and

SYMBICORT 100 TURBUHALER and SYMBICORT 200 TURBUHALER are available in 60 or 120 dose pack sizes.


Warnings and Precautions

Patients with asthma:

  • A large US clinical trial showed an increased risk of asthma related death and serious respiratory-related outcomes in patients who used salmeterol (a long-acting bronchodilator) in addition to their usual asthma therapy, in comparison with those who used placebo in addition to their usual asthma therapy. One of the medications in SYMBICORT TURBUHALER is formoterol fumarate dihydrate (also known as OXEZE), which is a different long-acting bronchodilator. Although similar findings have not been seen with formoterol fumarate dihydrate, the risks associated with salmeterol may also apply to other long-acting bronchodilator drugs including formoterol fumarate dihydrate.

  • SYMBICORT TURBUHALER should only be used when your doctor decides that other asthma medications (i.e. inhaled glucocorticosteroids along with an as needed relief medication) are not helping you enough, or that you need two maintenance medications to control your asthma. SYMBICORT TURBUHALER should not be the first medication you use, unless advised by your doctor.

BEFORE you use SYMBICORT TURBUHALER talk to your doctor or pharmacist if:

  • you have health problems now or have had in the past, especially if you have any problems with your heart, high blood sugar (diabetes), low blood potassium or any problems with your thyroid gland, or if you suffer from seizures (epilepsy).

  • you suffer from severe liver problems (e.g., cirrhosis).

  • you take other medicines, including those you have bought without a prescription. Certain types of medicines, for example beta-blockers, [some medicines for heart conditions (propranolol), high blood pressure (atenolol) or eye drops (timolol)] may reduce or block the effect of SYMBICORT TURBUHALER when taken at the same time. As well, some medicines used to treat fungal infections (ketoconazole, itraconazole) or ritonavir (medication used to treat HIV infection or AIDS) may alter the effect of SYMBICORT TURBUHALER.

  • you take, or have taken steroid medicines within the past several months.

  • you have ever had a bad, unusual or allergic reaction to budesonide, formoterol or lactose or to other medicines for breathing problems.

  • you are pregnant, plan to become pregnant or are breast-feeding.


Interactions with Symbicort

Drugs that may interact with SYMBICORT TURBUHALER include: beta-blockers (propranolol, atenolol, timolol), ketoconazole, itraconazole and ritonavir.


Proper Use of Symbicort

The dosage of SYMBICORT TURBUHALER is individual. It should be taken regularly (every day), even when you have no symptoms.

Follow your doctor's instructions carefully. Asthma and COPD therapy will differ from person to person and therefore your prescribed treatment may be different from the information contained in this leaflet.

Patients with Asthma

Treatment with SYMBICORT should not be initiated to treat an asthma attack.

For the treatment of asthma, your doctor will instruct you to use SYMBICORT TURBUHALER in one of two ways, as SYMBICORT maintenance therapy or as SYMBICORT maintenance and reliever therapy. Each of these treatment plans is described below.

SYMBICORT Maintenance Therapy for asthma

You take a regular daily dose from SYMBICORT TURBUHALER. In addition, you use a separate inhaler, containing a fast-acting bronchodilator (airway-widening medicine) for relief of asthma symptoms. This means that you need two separate inhalers.

Adults and adolescents (12 years and older):

  • 1-2 inhalations SYMBICORT 100 TURBUHALER once or twice daily. The maximum recommended daily maintenance dose is 4 inhalations.

or

  • 1-2 inhalations SYMBICORT 200 TURBUHALER once or twice daily. The maximum recommended daily maintenance dose is 4 inhalations.

Always carry your fast-acting bronchodilator (rescue medication) with you for relief of symptoms.

During periods of worsening of asthma, the dose may temporarily be increased up to a maximum of 4 inhalations of SYMBICORT 100 TURBUHALER or SYMBICORT 200 TURBUHALER twice daily.

Do NOT exceed the dose prescribed by your doctor.

SYMBICORT Maintenance and Reliever Therapy (SYMBICORT SMART) for asthma

You take a regular daily maintenance dose of SYMBICORT TURBUHALER, and also use SYMBICORT TURBUHALER if you need extra doses for relief of asthma symptoms. This means that you always have SYMBICORT TURBUHALER available for symptom relief.

Adults and adolescents (12 years and older):

  • 1-2 inhalations SYMBICORT 100 TURBUHALER twice daily or 2 inhalations once daily. You should take 1 additional inhalation as-needed if you feel symptoms. If symptoms persist after a few minutes, an additional inhalation should be taken. Not more than 6 inhalations should be taken on any single occasion. The maximum recommended daily dose is 8 inhalations.

or

  • 1-2 inhalations SYMBICORT 200 TURBUHALER twice daily or 2 inhalations once daily. You should take 1 additional inhalation as-needed if you feel symptoms. If symptoms persist after a few minutes, an additional inhalation should be taken. Not more than 6 inhalations should be taken on any single occasion. The maximum recommended daily dose is 8 inhalations.

Always carry SYMBICORT TURBUHALER with you. You should use extra doses as needed to relieve your asthma symptoms, including periods when your asthma gets worse.

Do not exceed the maximum total number of daily inhalations (8 inhalations/day). If you exceed 8 inhalations/day please seek medical attention.

Patients with COPD

For the maintenance treatment of COPD, your doctor will instruct you to use SYMBICORT TURBUHALER as follows:

Adults (18 years and older)

  • 2 inhalations SYMBICORT 200 TURBUHALER twice daily. The maximum recommended daily dose is 4 inhalations.

A. How to prepare a new inhaler for use

(See package insert for illustrations.)

Before you start using SYMBICORT TURBUHALER for the first time it is important that you read the instructions below and follow them carefully.

TURBUHALER is an inhaler from which very small amounts of powder are administered. When you breathe in through TURBUHALER the powder is delivered to the lungs. It is therefore important that you inhale forcefully and deeply through the mouthpiece.

SYMBICORT TURBUHALER is very easy to use.

If you follow the instructions below, you will receive the medication.

Preparation before first use of NEW inhaler

Before using your inhaler for the first time you need to prepare the inhaler for use. The preparation does not need to be repeated even if your inhaler is not used regularly.

  1. Unscrew and lift off the cover. You may hear a rattling sound. This is normal.

  2. Hold the inhaler upright with the red grip downwards. Turn the red grip as far as it will go in one direction and then turn it back as far as it will go in the opposite direction. Perform this procedure twice.

 

Technical Information