Precautions
When topical corticosteroids are applied for a prolonged period of time, sufficient systemic absorption can suppress the hypothalamic-pituitary-adrenal axis. Growth suppression may also occur.
Although topical steroids have not been reported to have an adverse effect on pregnancy, the safety of their use has not absolutely been established. Therefore, use with care during pregnancy.
Supplied
Each mL contains: methylprednisolone acetate 2.5 mg, neomycin sulfate 2.5 mg, aluminum chlorhydroxide complex 100 mg and colloidal sulfur 50 mg. Nonmedicinal ingredients: butylparaben, cetyl palmitate, lexemul ar, methylcellulose, methylparaben, perfume oil, polyethylene glycol, polysorbate 80, polysorbate 85 and propylene glycol. Plastic squeeze bottles of 25 and 75 mL.
Warnings
No data supplied by the manufacturer.
Contraindications
In tuberculosis of the skin, herpes simplex, vaccinia, varicella and in other cutaneous infections which do not respond to neomycin. Known hypersensitivity to any of the components.
Adverse Effects
The following local adverse reactions have been reported with topical corticosteroids, either with or without occlusive dressings: burning sensation, itching, irritation, dryness, folliculitis, secondary infection, skin atrophy, striae, hypertrichosis, acneiform eruptions, allergic contact dermatitis, laceration of the skin and hypopigmentation.
Indications
For control of acne vulgaris in the adolescent and young adult. Also in some cases of acne rosacea and seborrheic dermatitis.
Dosage
After careful cleansing of the affected skin to minimize the possibility of introducing infection, Neo-Medrol Acne Lotion should be applied sparingly to the affected areas once or twice a day initially. Care should be taken to avoid contact with the eyes. The frequency of application will vary from patient to patient, depending on their susceptibility to the drying effect of the lotion, and may have to be reduced to every other day in some patients.
Overdose
For management of a suspected drug overdose, CPhA recommends that you contact your regional Poison Control Centre. See the eCPS Directories section for a list of Poison Control Centres.
No data supplied by the manufacturer.
